Section5:Abbreviations

[L] - Radioligand Concentration
[R] - Receptor Concentration
[RL] - Concentration of Receptor-Ligand complex
Kd - equilibrium dissociation constant for radioligand ([RL] yielding Bmax/2)
Ki - equilibrium dissociation constant for an unlabeled compound
IC50 - concentration of unlabeled drug which results in 50% inhibition of binding activity
kon - association rate constant
koff - dissociation rate constant
kobs - observed association rate constant
Bmax - maximum number of binding sites
NPE - Non-proximity Effects
NSB - Nonspecific binding
Ki C-P = Ki Cheng-Prusoff
Ki T-B = Ki Tight-Binding